Fixed-dosed Kcentra protocol starts May 8

29 Apr 2018

For patients needing warfarin reversal

 

Recently, the Pharmacy and Therapeutics Committee approved a protocol implementing fixed-dosed Kcentra for patients presenting in need of warfarin reversal. We will be implementing this on May 8, 2018.

Steps:

• A baseline INR will be drawn.
• An initial dose of 1,500 units of Kcentra and 2 mg of vitamin K will be ordered.
• A second INR will be drawn after the Kcentra is given.
• If the second INR is > 1.5, the pharmacist will follow up with primary physician to determine if additional Kcentra is needed, then order an additional dose according to the package insert dosing.
• Further information (including the protocol) can be found on the Anticoagulation Reversal Guideline, under “Warfarin. ”

If you have questions contact Matt Tanner in Pharmacy at Matthew.Tanner@SalemHealth.org or 503-814-2048.